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Research funding: None declared.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Informed consent: Written informed consent is not required due to the fact that NBS is mandatory by law.
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Ethical approval: The local Institutional Review Board deemed the study exempt from review due to the fact the newborn screening is mandatory by national law (167/2016) and regional law (DGR 909/2018).
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