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Licensed Unlicensed Requires Authentication Published by De Gruyter November 23, 2021

The pronounced decline of anti-SARS-CoV-2 spike trimeric IgG and RBD IgG in baseline seronegative individuals six months after BNT162b2 vaccination is consistent with the need for vaccine boosters

  • Gian Luca Salvagno , Brandon M. Henry , Laura Pighi , Simone De Nitto , Gianluca Gianfilippi and Giuseppe Lippi ORCID logo EMAIL logo

Corresponding author: Prof. Giuseppe Lippi, Section of Clinical Biochemistry, University Hospital of Verona, Piazzale L.A. Scuro, 10, 37134 Verona, Italy, Phone: +39 045 8122970, Fax: +39 045 8124308, E-mail:

Acknowledgments

The authors are thankful to the entire staff of the Pederzoli Hospital of Peschiera del Garda (Verona, Italy) for accepting to participate to this study.

  1. Research funding: The authors received no funding for this work.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

  4. Informed consent: Informed consent was obtained from all subjects included in this study.

  5. Ethical approval: The study protocol (59COVIDCESC; November 3, 2021) was cleared by the Ethics Committee of the Provinces of Verona and Rovigo. All subjects were informed of the study and voluntarily agreed to participate, providing a written consent.

References

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Received: 2021-11-08
Accepted: 2021-11-12
Published Online: 2021-11-23
Published in Print: 2022-01-27

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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