Acknowledgments
The authors would like to acknowledge the Haematology Department at Cork University Hospital, in particular Medical Laboratory Scientists, for encouragement, discussion, and support throughout this study. The authors would also like to gratiously thank Mr. Bradley Williams for technical support.
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Research funding: None declared.
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Author contributions: J.V. Harte, and V. Mykytiv conceptualized the study, designed the methodology, and were responsible for project administration; C. Grieve and C. Hooton were responsible for haemocytometric and microbiological data extraction; J.V. Harte and C.Ní Choileáin were responsible for data curation and formal analysis; J.V. Harte wrote the original manuscript. J.V. Harte revised the manuscript for final publication. All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Informed consent: All volunteers who donated blood for the determination of haemocytometric reference intervals provided informed consent.
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Ethical approval: The study protocol for the determination of haemocytometric reference intervals was approved by the Clinical Research Ethics Committee of the Cork Teaching Hospitals (reference number: ECM4(a) 9/3/2021 – COVID 19). The retrospective review of anonymised data was also approved by the Clinical Research Ethics Committee of the Cork Teaching Hospitals (reference number: ECM4(e) 9/2/2021 – COVID 19). The retrospective review of anonymised data based on haemocytometric and microbiological data extracted from the Laboratory Information System did not require informed consent, in accordance with approval by the Clinical Research Ethics Committee of the Cork Teaching Hospitals.
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Data availability: The full dataset of haemocytometric parameters in patients with COVID-19, including all cell population data (CPD) parameters, is available from the authors upon reasonable request.
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