-
Research funding: None declared.
-
Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
-
Competing interests: Authors state no competing of interest.
-
Informed consent: Not applicable.
-
Ethical approval: Not applicable.
References
1. Mandrile, G, Barella, S, Giambona, A, Gigante, A, Grosso, M, Perrotta, S, et al.. First and second level haemoglobinopathies diagnosis: best practices of the Italian society of thalassemia and haemoglobinopathies (SITE). J Clin Med 2022;11:5426. https://doi.org/10.3390/jcm11185426.Search in Google Scholar PubMed PubMed Central
2. Wajcman, H, Moradkhani, K. Abnormal haemoglobins: detection & characterization. Indian J Med Res 2011;134:538–46.Search in Google Scholar
3. Dasauni, P, Chhabra, V, Kumar, G, Kundu, S. Advances in mass spectrometric methods for detection of hemoglobin disorders. Anal Biochem 2021;629:114314. https://doi.org/10.1016/j.ab.2021.114314.Search in Google Scholar PubMed
4. Théberge, R, Dikler, S, Heckendorf, C, Chui, DHK, Costello, CE, McComb, ME. MALDI-ISD mass spectrometry analysis of hemoglobin variants: a top-down approach to the characterization of hemoglobinopathies. J Am Soc Mass Spectrom 2015;26:1299–310. https://doi.org/10.1007/s13361-015-1164-4.Search in Google Scholar PubMed PubMed Central
5. De Benedittis, S, Gaspari, M, Magariello, A, Spadafora, P, Citrigno, L, Romeo, N, et al.. LC-MALDI-TOF ISD MS analysis is an effective, simple and rapid method of investigation for histones characterization: application to EBV lymphoblastoid cell lines. J Mass Spectrom 2021;56:e4712. https://doi.org/10.1002/jms.4712.Search in Google Scholar PubMed
6. Ju, Y. Applications of matrix-assisted laser desorption ionization in-source decay mass spectrometry. Adv Exp Med Biol 2019;1140:45–54. https://doi.org/10.1007/978-3-030-15950-4_3.Search in Google Scholar PubMed
7. Jain, N, Kesimer, M, Hoyer, JD, Calikoglu, AS. Hemoglobin Raleigh results in factitiously low hemoglobin A1c when evaluated via immunoassay analyzer. J Diabet Complicat 2011;25:14–8. https://doi.org/10.1016/j.jdiacomp.2009.09.004.Search in Google Scholar PubMed
8. Chen, D, Crimmins, DL, Hsu, FF, Lindberg, FP, Scott, MG. Hemoglobin Raleigh as the cause of a falsely increased hemoglobin A1C in an automated ion-exchange HPLC method. Clin Chem 1998;44:1296–301.Search in Google Scholar
9. Rai, DK, Landin, B, Griffiths, WJ, Alvelius, G. Identification of N-terminal acetylation in Hb Raleigh (beta1Val-->Ac-Ala) by electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom RCM 2002;16:1793–6. https://doi.org/10.1002/rcm.774.Search in Google Scholar PubMed
10. Moo-Penn, WF, Bechtel, KC, Schmidt, RM, Johnson, MH, Jue, DL, Schmidt, DE, et al.. Hemoglobin Raleigh (β1 valine →acetylalanine). Structural and functional characterization. Biochemistry 1977;16:4872–9.10.1021/bi00641a019Search in Google Scholar PubMed
11. Bry, L, Chen, PC, Sacks, DB. Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin. Clin Chem 2001;47:153–63. https://doi.org/10.1093/clinchem/47.2.153.Search in Google Scholar
© 2023 Walter de Gruyter GmbH, Berlin/Boston
